| | | | | |
| 27-Apr-23 17:00
Estadio Ka’arendy
Ref:Juliadoza
Lm 1:Miranda, G
Lm 2:Sosa, C
|
 | General Caballero JLM
Báez, C 23' 
| 1 - 0 | Tacuary
|
| |
| 27-Apr-23 19:30
Manuel Ferreira
Ref:Benitez, C
Lm 1:Candia
Lm 2:Villagra
|
 | Olimpia
Ortiz, R 64'
| 1 - 1 | Trinidense
41' Delvalle, P
|
| |
| 28-Apr-23 18:00
Estadio General Pablo Rojas
Ref:López, D
Lm 1:Onieva
Lm 2:Gaona
|
 | Cerro Porteño
Rivas, Leo 30'
Bobadilla, D 66'
| 2 - 0 | Guaireña FC
|
| |
| 28-Apr-23 20:30
Rogelio Livieres
Ref:Ojeda, D
Lm 1:Cuevas, J
Lm 2:Aranda
|
 | Guaraní
Rivarola 51'
| 1 - 0 | Resistencia
|
| |
| 29-Apr-23 18:00
Estadio Tigo La Huerta
Ref:Díaz de Vivar
Lm 1:Britos
Lm 2:Medina, H
|
 | Libertad
González, Enso 41'
Sanabria, L (1999) 45'
| 2 - 1 | Nacional
71' Ocampos, C
|
| |
| 01-May-23 18:00
Estadio Defensores del Chaco
Ref:López, J
Lm 1:Cañete
Lm 2:Fernández, N
|
 | Sportivo Ameliano
Sarquis 66'
Vera, Elvio 88'
| 2 - 0 | Sportivo Luqueño
|
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