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| 15-Sep-23 17:00
Parque del Guairá
Ref:Romero, B
Lm 1:Cañete
Lm 2:Candia
|
 | Guaireña FC
Verdún 45'
Borja, E 87'
| 2 - 0 | Trinidense
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| 15-Sep-23 19:30
Arsenio Erico
Ref:Méndez, J
Lm 1:Saldivar, M
Lm 2:Fernández, N
|
 | Nacional
Aguilar, GÁ 68'
Espínola, Héctor 93' 
Núñez, Claudio 95' 
| 2 - 1 | Sportivo Luqueño
51' Fernández, Diego (2002)
 93' Castro, Matías (1991dec)
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| 16-Sep-23 16:30
Luis Alfonso Giagni
Ref:López, D
Lm 1:Onieva
Lm 2:Gaona
|
 | Tacuary
| 0 - 4 | Libertad
48' Cardozo, O
63' Merlini, B
67' Villalba, H
93' Barboza, Alexander
|
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| 16-Sep-23 19:00
Manuel Ferreira
Ref:Díaz de Vivar
Lm 1:Britos
Lm 2:Weiler
|
 | Olimpia
Silva, Alejandro 79'
Romero, Manuel 81'
Montenegro, B 94'
| 3 - 1 | General Caballero JLM
7' Machuca, M
|
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| 17-Sep-23 16:30
Luis Alfonso Giagni
Ref:Quiñónez
Lm 1:Cuevas, J
Lm 2:Villagra
|
 | Sportivo Ameliano
Vera, Elvio 52'
| 1 - 2 | Resistencia
71' Moreira, J
79' Díaz, Estifen
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| 17-Sep-23 19:00
Rogelio Livieres
Ref:Benitez, J
Lm 1:Cardozo
Lm 2:Medina, H
|
 | Guaraní
Camacho, N 55' 
| 1 - 0 | Cerro Porteño
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