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28-Sep-21 12:00
NTK Bannikov
Ref: Frischer
|
 | Shakhtar Donetsk 
| 0 - 1 |  Inter Milan
30' Casadei, C
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28-Sep-21 14:00
Stadion am Cottaweg
Ref: Chinkov
|
 | RB Leipzig 
Friedrich, R 32'
| 1 - 4 |  Club Brugge
36' Audoor
61' Sandra
78' Sandra
94' Talbi, C
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28-Sep-21 14:30
Centro Sportivo Peppino Vismara
Ref: Zelinka
|
 | AC Milan
Gala, A (2004) 44'
| 1 - 1 |  Atletico Madrid
22' El Jebari
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28-Sep-21 14:30
Estádio Dr Jorge Sampaio
Ref: Lardot
|
 | FC Porto 
Abreu, D 69'
| 1 - 1 |  Liverpool
80' Frauendorf
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28-Sep-21 14:30
De Toekomst
Ref: Kjærsgaard
|
 | Ajax Amsterdam 
Hlynsson, K 35'
van Axel Dongen 55'
Misehouy 78'
| 3 - 1 |  Beşiktaş
82' Yağcı, K
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28-Sep-21 15:30
Brackel Training Ground
Ref: Lukjančukas
|
 | Borussia Dortmund
| 0 - 0 | Sporting Lisbon
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28-Sep-21 16:00
Stade Georges Lefèvre
Ref: Farkas
|
 | Paris Saint-Germain FC 
Xavi Simons 68' 
| 1 - 1 | Manchester City
30' Charles, Shea
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28-Sep-21 16:00
Alfredo di Stéfano
Ref: Høvdanum
|
 | Real Madrid
Javi Villar 37'
Iglesias, Bruno 51'
Iglesias, Bruno 71'
Landabaso 79'
| 4 - 1 |  Sheriff Tiraspol
 og 47' Pau, FB
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28-Sep-21 18:00
LFF stadionas
Ref: Luís Teixeira
|
 | Žalgiris Vilnius
| 0 - 3 |  Maccabi Haifa
5' Laish
62' Zaga
86' Razon
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28-Sep-21 19:30
Ibrox Stadium
Ref: Diamantopoulos
|
 | Rangers FC 
Ure 11'
McCausland 65'
McCausland 81'
| 3 - 0 |  Hammarby IF
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29-Sep-21 11:00
Smena Stadium
Ref: Kuchin
|
 | Zenit Saint Petersburg 
Mikhailovskii 43'
Rodionov, I 76'
Zigangirov 91'
| 3 - 2 | Malmö FF
11' Björkqvist
89' Bjerkebo
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29-Sep-21 13:00
Centro Sportivo Bortolotti
Ref: Jorgji
|
 | Atalanta
Oliveri 20'
Omar, S 41'
Lozza 55'
| 3 - 0 |  Young Boys Bern
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29-Sep-21 14:00
Celtnieks Stadium
Ref: Pechanec
|
 | BFC Daugavpils 
| 0 - 4 |  FC Minsk
27' Dushevskiy
 34' Kasarab
58' Dushevskiy
68' Malashevich
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29-Sep-21 14:00
Leigh Sports Village
Ref: Arnason
|
 | Manchester United
Álvaro Carreras 72'
| 1 - 4 | Villarreal
5' Torrents
22' Pascual, J
28' Foubert-Jacquemin
45' Alonso, R (2003)
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29-Sep-21 14:00
Untersberg-Arena
Ref: Al Hakim
|
 | Red Bull Salzburg 
Šimić, R 32'
Šimić, R 48'
Kameri 65'
| 3 - 1 | Lille OSC
89' Said, Y
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29-Sep-21 15:00
Gradski stadion Ugljevik
Ref: Sabotic
|
 | FK Zvijezda 09 
| 0 - 1 | Trabzonspor
45' Tuğ
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29-Sep-21 16:00
GSP Stadium
Ref: Jakimovski
|
 | APOEL Nicosia 
Satsias, G 13'
| 1 - 1 | FC Kairat
5' Omatay
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29-Sep-21 16:00
FC Bayern Campus
Ref: Farrugia Cann
|
 | Bayern München
| 0 - 4 | Dynamo Kyiv
33' Diallo, Samba (2003)
57' Diallo, Samba (2003)
59' Voloshyn, N
85' Skrypnyk, I
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29-Sep-21 16:00
Caixa Futebol Campus
Ref: Papapetrou
|
 | Benfica
João Resende 45'
Ndour 49'
João Resende 56'
Martim Neto 68'
| 4 - 0 | Barcelona
|
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29-Sep-21 16:00
AOK Stadion
Ref: Schnyder
|
 | VfL Wolfsburg
Ambros, L 27'
| 1 - 1 | Sevilla
65' Diego Talaverón
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29-Sep-21 16:00
Juventus Training Ground
Ref: António Nobre
|
 | Juventus
Soulé 27'
Mulazzi, G 45'
Galante, T 89'
| 3 - 1 | Chelsea
73' Wareham
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29-Sep-21 17:00
Vasil Levski National Stadium
Ref: Karakó
|
 | Septemvri Sofia
Stoichkov, Stoyan 44'
Avramov, I (2004) 45'
Aleksandrov, S 80'
| 3 - 0 | Akademia e Futbollit
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29-Sep-21 17:00
Gabala City Stadium
Ref: Kopievsky
|
 | Gabala FK 
| 0 - 4 | AZ Alkmaar
15' Koster, N
54' Schouten, L
59' Koster, N
78' Daal, R
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29-Sep-21 18:00
Stadion Florian Krygier
Ref: Jäger
|
 | Pogoń Szczecin 
Fornalczyk 39'
Bąk, M (2003) 45'
Grzelka 92'
| 3 - 0 | Deportivo La Coruña
|
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29-Sep-21 18:00
Hidegkuti Nándor Stadium
Ref: Laforge
|
 | MTK Budapest
Vasvári 5'
Vancsa 25'
Vancsa 46'
| 3 - 1 | Sparta Praha
20' Šilhart
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29-Sep-21 18:00
Rhein Energie Stadion
Ref: Zebec
|
 | 1. FC Köln
Schmid, Max 5'
Schwirten 47'
| 2 - 4 | RC Genk
36' Diawara, Sekou
43' John, Kelvin
45' John, Kelvin
 58' Németh, A
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29-Sep-21 18:00
Staionul Municipal
Ref: Hamiti
|
| FK Csíkszereda Miercurea Ciuc 
| 0 - 2 | Angers SCO
17' Boma
og 90' Gergely
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29-Sep-21 19:00
Toumba Stadium
Ref: San
|
 | PAOK
Gustavo Varela 6'
| 1 - 5 |  MŠK Žilina
27' Kaprálik
45' Sauer, Mario
50' Jambor, T
63' Jambor, T
91' Kaprálik
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29-Sep-21 19:00
Športni park Domžale
Ref: Milanović
|
 | NK Domžale 
Černe 28'
| 1 - 2 | Empoli
8' Ekong, E
75' Baldanzi
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29-Sep-21 19:45
Richmond Park
Ref: Kristjánsson, Í
|
 | St Patrick's Athletic 
McCormack, B 92'
| 1 - 2 | Red Star Belgrade
3' Lazetić, M
45' Lazetić, M
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30-Sep-21 14:00
City Stadium Tetovo
Ref: Popov, N
|
 | FK Škendija
| 0 - 2 | HNK Hajduk Split
29' Čuić, F
56' Čuić, F
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30-Sep-21 18:00
Lerkendal stadion
Ref: Owen
|
 | Rosenborg BK 
Kvendbø 23'
Evjen-Brostrøm 90'
| 2 - 4 | FC Midtjylland
22' Fraulo
46' Hansen, Mads (2002)
54' Şimşir, Aral
65' Texel
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