| Lineups found Starting lineup changes since last game |
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| September 2010 |
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| Coach Wenger since 01-Oct-96 |
| M.1 | 15-Sep | | Braga | | 6-0 | 4-2-3-1 | |
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 19-Sep to 18-Oct Fàbregas hamstring injury |
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 20-Sep to 22-Sep Song, A red card ban (1 match) |
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| 22-Sep to 27-Sep Gibbs, K bruised foot |
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| 26-Sep to 15-Dec Almunia elbow injury |
| M.2 | 28-Sep | away | Partizan | | 1-3 | 4-1-4-1 | In:Fabi'ki, Djourou, Gibbs, Rosický, Denilson, Out:Almunia, Koscielny, Clichy, Nasri, Fàbregas, |
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| 29-Sep to 13-Oct Gibbs, K calf injury |
| October 2010 |
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| 08-Oct to 23-Oct Sagna thigh strain |
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| 15-Oct to 22-Oct Koscielny back injury |
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| 17-Oct to 17-Dec Diaby ankle injury recurrence |
| M.3 | 19-Oct | | Shakhtar | | 5-1 | 4-2-3-1 | In:Eboue, Clichy, Fàbregas, Nasri, Out:Sagna, Gibbs, Denilson, Arshavin, |
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| November 2010 |
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| 23-Oct to 31-Oct Wilshere domestic red card ban (3 matches) |
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| 28-Oct to 12-Nov Gibbs, K medial knee ligament injury |
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| 31-Oct to 31-Dec Randall broken collarbone |
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| 31-Oct to 04-Nov Fàbregas hamstring injury |
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| 31-Oct to 09-Nov Denilson groin injury |
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| 01-Nov to 28-Nov Ramsey match fitness |
| M.4 | 03-Nov | away | Shakhtar | | 2-1 | 4-2-3-1 | In:Eastmond, Walcott, Bendtner, Out:Song, A, Fàbregas, Chamakh, |
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| 09-Nov to 15-Nov Koscielny red card ban (2 matches) |
| M.5 | 23-Nov | away | Braga | | 2-0 | 4-2-3-1 | In:Gibbs, Denilson, Fàbregas, Out:Clichy, Eastmond, Nasri, |
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| 24-Nov to 29-Nov Eboue bruised knee |
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| 24-Nov to 12-Dec Fàbregas hamstring injury |
| December 2010 |
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| 28-Nov to 01-Dec Squillaci knee injury |
| M.6 | 08-Dec | | Partizan | | 3-1 | 4-2-3-1 | In:Sagna, Koscielny, Song, A, Nasri, v Persie, Arshavin, Chamakh, Out:Eboue, Djourou, Wilshere, Walcott, Fàbregas, Rosický, Bendtner, |
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| February 2011 |
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| 09-Dec to 08-Jan Gibbs, K sprained ankle |
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| 16-Dec to 23-Jan Almunia ankle injury |
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| 28-Dec to 30-Dec Fàbregas 5 yellow card ban (1 match) |
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| 29-Dec to 15-Jan Mannone thigh injury |
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| 30-Dec to 26-Jan Diaby calf strain |
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| 07-Jan to 16-Jan Sagna red card ban (3 matches) |
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| 09-Jan to 29-Jan Squillaci hamstring strain |
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| 11-Jan to 26-Jan Rosický illness |
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| 31-Jan to 15-Feb Nasri hamstring strain |
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| 31-Jan to 02-Feb Squillaci red card ban (1 match) |
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| 31-Jan to 11-Feb Denilson hamstring strain |
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| 02-Feb to 06-Feb Song, A thigh injury |
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| 10-Feb to 24-Feb Diaby calf injury |
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| 11-Feb to 13-Feb Diaby domestic red card ban (1 of 3 matches) |
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| 11-Feb to 15-Feb Rosický groin injury |
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| 14-Feb to 17-Feb Sagna Champions League red card ban (1 match) |
| M.7 | 16-Feb | | Barcelona | | 2-1 | 4-2-3-1 | In:Szczęsny, Eboue, Djourou, Clichy, Wilshere, Walcott, Fàbregas, Out:Fabi'ki, Sagna, Squillaci, Gibbs, Denilson, Arshavin, Chamakh, |
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| 17-Feb to 21-Feb Djourou back injury |
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| 17-Feb to 26-Feb van Persie hamstring injury |
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| 17-Feb to 26-Feb Koscielny back injury |
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| 19-Feb to 24-Feb Diaby domestic 3 game red card ban (matches 2 and 3) |
| March 2011 |
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| 24-Feb to 06-Mar Fàbregas hamstring injury |
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| 24-Feb to 31-Mar Walcott sprained ankle |
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| 28-Feb to 07-Mar van Persie knee injury |
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| 28-Feb to 03-Mar Koscielny hamstring injury |
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| 28-Feb to 28-Mar Song, A knee injury |
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 03-Mar to 03-Mar Shea, J recalled from loan due to injury crisis at Arsenal |
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| 06-Mar to 15-Apr Mannone thigh injury |
| M.8 | 08-Mar | away | Barcelona | | 3-1 | 4-2-3-1 | In:Sagna, Diaby, Rosický, Out:Eboue, Song, A, Walcott, |
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| 09-Mar to 16-Apr Szczęsny dislocated finger |
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| 09-Mar to 25-Mar Fàbregas hamstring injury |
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| 13-Mar to 16-Apr Djourou dislocated shoulder |
| April 2011 |
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| 18-Mar to 20-Mar Vela ineligible against parent club |
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| 20-Mar to 03-Apr Denilson toe injury |
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| 27-Mar to 03-Apr Ramsey groin injury |
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| 03-Apr to 11-Apr Song, A knee injury |
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| 16-Apr to 02-May Vermaelen match fitness |
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| 21-Apr to 21-May Diaby calf injury |
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| 24-Apr to 02-May Mannone damaged shoulder |
| May 2011 |
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| 30-Apr to 25-May Fàbregas ankle injury |
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| 02-May to 09-May Djourou ankle injury |
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| 02-May to 09-May Nasri hamstring injury |
| Color References: GK, DF, DM, MF, FW , Unknown Pos |