| Lineups found Starting lineup changes since last game |
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| August 2020 |
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| Coach Arteta since 22-Dec-19 |
| September 2020 |
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 30-Aug to 30-Sep Cédric Calf Injury |
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| 01-Sep to 18-Sep David Luiz Neck Injury |
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| 11-Sep to 17-Oct Smith-Rowe right shoulder injury |
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| 12-Sep to 18-Sep Xhaka Ankle Injury |
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| 13-Sep to 27-Sep Tierney, K Groin Injury |
| M.3 | 23-Sep | away | Leicester | | 0-2 | 3-4-3 | |
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| October 2020 |
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| M.4 | 01-Oct | away | Liverpool | | 0-0 | 4-3-3 | In:Cédric, Gabriel, D Ceballos, Xhaka, Out:D Luiz, Mait'es, Elneny, Nelson, |
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| December 2020 |
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| 17-Oct to 31-Oct Holding Thigh Injury |
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| 17-Oct to 28-Oct Willian Calf Injury |
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| 18-Oct to 24-Oct Dani Ceballos Ankle Injury |
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| 25-Oct to 04-Nov David Luiz Thigh Injury |
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| 30-Oct to 21-Nov Nelson, Reiss Knee Injury |
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| 15-Nov to 02-Dec Elneny Covid-19 |
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| 16-Nov to 02-Dec Kolašinac Covid-19 |
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 23-Nov to 15-Dec Pépé Domestic Red Card Ban |
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| 29-Nov to 15-Dec David Luiz Head Injury |
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| 03-Dec to 08-Jan Nelson, Reiss Head Injury |
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| 04-Dec to 16-Dec Kolašinac Knock |
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| 14-Dec to 25-Dec Xhaka Red Card Ban |
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| 14-Dec to 18-Dec Bellerín Yello Card Accumulation |
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| 17-Dec to 21-Dec Gabriel, Magalhães Red Card Ban |
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| 20-Dec to 01-Jan David Luiz Illness |
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| 20-Dec to 01-Jan Willian Illness |
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| 22-Dec to 25-Dec Gabriel Martinelli Calf Injury |
| M.5 | 22-Dec | | Man.City | | 1-4 | 3-4-3 | In:Runa'on, Mustafi, Elneny, Mait'es, Lacazette, G Mart'li, Out:Leno, Holding, Xhaka, Saka, B, Nketiah, Pépé, |
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| 23-Dec to 17-Jan Gabriel, Magalhães Covid-19 |
| January 2021 |
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| 29-Dec to 01-Jan Saka, B Ankle Injury |
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| 29-Dec to 18-Jan Gabriel Martinelli Ankle Injury |
| April 2021 |
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| 10-Jan to 18-Jan Tierney, K Muscle Injury |
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| 14-Jan to 01-Feb Dani Ceballos Calf Injury |
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| 19-Jan to 17-Feb Tierney, K Calf Injury |
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| 26-Jan to 29-Jan Smith-Rowe Knock |
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| 03-Feb to 13-Feb David Luiz Red Card Ban |
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| 03-Feb to 13-Feb Leno Red Card Ban |
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| 21-Feb to 27-Feb Holding Head Injury |
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| 28-Feb to 06-Mar Smith-Rowe Groin Injury |
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| 15-Mar to 02-Apr Willian Calf Strain |
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| 21-Mar to 03-Apr Saka, B Thigh Injury |
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| 28-Mar to 03-Apr Smith-Rowe Thigh Injury |
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| 29-Mar to 03-Apr Xhaka Knock |
| Color References: GK, DF, DM, MF, FW , Unknown Pos |