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Defensa y Justicia Substitutions at Copa Libertadores 2021
| Most In | | Most Out | | Escalante, Lautaro | 3 times | 21 minutes avg | | Merentiel | 3 | 17 | | Rius | 2 | 24 | | Tripichio, N | 2 | 38 | | Hachen | 2 | 42 | | Lencina, K | 1 | 0 | | Ortiz, Tomás (2000) | 1 | 1 | | Gallardo, N | 1 | 16 | | Meza, F | 1 | 45 | | Brítez, E | 1 | 35 | | Pizzini | 1 | 20 | | Loaiza, R | 1 | 14 | | Paredes, FE | 1 | 1 | | Barrios | 1 | 10 | | Rivero, B | 1 | 0 |
| | | | 8 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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