| Lineups found Starting lineup changes since last game |
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| November 2019 |
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| Coach Marco Silva since 31-May-18 |
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 23-Nov to 04-Dec Walcott Illness |
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| 24-Nov to 14-Dec Coleman, S Knock |
| December 2019 |
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| Coach Ferguson, Duncan since 05-Dec-19 |
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| 05-Dec to 14-Dec Mina, Y Tight Hamstring |
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| 07-Dec to 25-Dec Walcott Calf Strain |
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| 07-Dec to 14-Dec Digne Tight Groin |
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| 08-Dec to 01-Jan Schneiderlin Calf Strain |
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| 08-Dec to 20-Dec Sigurðsson, G Knock |
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| 08-Dec to 20-Dec Sidibé, Djibril (1992) Illness |
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| 15-Dec to 20-Dec Digne Groin Injury |
| January 2020 |
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| Coach Ferguson, Duncan since 22-Dec-19 |
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| Coach Ancelotti since 22-Dec-19 |
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| Coach Ancelotti, D since 22-Dec-19 |
| M.5 | 05-Jan | away | Liverpool | | 1-0 | 3-4-2-1 | |
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| 12-Jan to 31-Jan Richarlison Knee Injury |
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| 12-Jan to 31-Jan Sigurðsson, G Groin Injury |
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| 12-Jan to 20-Jan Keane, M Stiff Neck |
| February 2020 |
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 02-Feb to 22-Feb Delph Red Card Ban (1 match) |
| March 2020 |
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| 08-Feb to 29-Feb Walcott Knee Injury |
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| 08-Feb to 22-Feb Bernard, Duarte Knock |
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| 09-Feb to 07-Mar Digne Muscle Injury |
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| 23-Feb to 17-May Schneiderlin Knee Injury |
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| 01-Mar to 17-May Coleman, S Thigh Injury |
| June 2020 |
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| 08-Mar to 17-May Bernard, Duarte Knee Injury |
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| 01-Jun to 05-Jul Sidibé, Djibril (1992) Foot Injury |
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| 02-Jun to 30-Jun Mina, Y Quad Injury |
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| 10-Jun to 08-Jul Walcott Abdominal Surgery |
| July 2020 |
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| 06-Jul to 15-Jul Holgate, M Calf Injury |
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| 12-Jul to 31-Jul Mina, Y Quad Strain |
| August 2020 |
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| Color References: GK, DF, DM, MF, FW , Unknown Pos |