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FC Cincinnati Substitutions at Major League Soccer 2021
| Most In | | Most Out | | Vázquez, B | 17 times | 14 minutes avg | | Medunjanin | 10 | 11 | | Harris, Calvin | 9 | 16 | | Stanko | 7 | 27 | | Hagglund | 6 | 20 | | Atanga, I | 6 | 18 | | Barreal | 6 | 27 | | Mokotjo | 5 | 17 | | Locadia | 3 | 27 | | Ordonez | 3 | 10 | | Valot | 3 | 13 | | Blackett, T | 3 | 17 | | Gyau | 3 | 28 | | Scott, K | 3 | 11 | | Cruz, A | 2 | 14 | | Kovačević, F | 2 | 15 | | Duvall | 2 | 29 | | Cameron, G | 2 | 38 | | Tytoń | 1 | 25 | | Acosta, Luciano | 1 | 28 | | Castillo, Edgar | 1 | 15 |
| | | Barreal | 14 times | 75 minutes avg | | Kubo, Yuya | 13 | 72 | | Medunjanin | 11 | 77 | | Atanga, I | 7 | 70 | | Vallecilla, E | 7 | 55 | | Cameron, G | 5 | 81 | | Cruz, A | 5 | 81 | | Castillo, Edgar | 5 | 67 | | Bailey, Z | 5 | 68 | | Mokotjo | 4 | 76 | | Stanko | 4 | 66 | | Brenner, SdS | 4 | 77 | | Valot | 3 | 63 | | Acosta, Luciano | 2 | 84 | | Pettersson, T | 1 | 91 | | Vermeer | 1 | 65 | | Hagglund | 1 | 70 | | Matarrita | 1 | 75 | | Scott, K | 1 | 57 | | Gyau | 1 | 45 |
| | 34 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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