| Lineups found Starting lineup changes since last game |
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| August 2009 |
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| Coach Prandelli since 01-Jul-05 |
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 15-Aug to 16-Sep De Silvestri right knee |
| November 2009 |
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| 22-Aug to 23-Aug Zanetti, C hallux bruise |
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| 29-Aug to 13-Sep Mutu right thigh |
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 15-Sep to 17-Sep Zanetti, C UEFA Champions League ban (1 match) |
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| 15-Sep to 17-Sep Ljajić UEFA Europa League ban (1 match) |
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| 24-Sep to 02-Oct Comotto right biceps femoris |
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| 24-Sep to 16-Oct Santana rectus femoris |
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| 28-Sep to 29-Sep Gilardino red card Champions League ban |
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| 23-Oct to 25-Oct Marchionni muscular pain |
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| 26-Oct to 06-Nov Natali biceps femoris muscle strain |
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| 27-Oct to 29-Oct Jørgensen, M (1975) gastroenteritis |
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| 27-Oct to 29-Oct Santana adductor muscle strain |
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| 31-Oct to 22-Nov Jovetić foot bruise |
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| 05-Nov to 16-Jan Gamberini biceps femoris muscle strain |
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| 05-Nov to 26-Nov Mutu meniscus |
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| 10-Nov to 22-Nov Montolivo 4th yellow card ban (1 match) |
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| 26-Nov to 29-Nov Donadel red card ban (1 match) |
| December 2009 |
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| 02-Dec to 06-Dec Zanetti, C 4th yellow card ban (1 match) |
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 02-Dec to 02-Dec Ljajić man utd decline option to sign |
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| 08-Dec to 16-Feb Zanetti, C patellar tendonitis |
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| 16-Dec to 12-Jan Marchionni tendonitis |
| January 2010 |
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| 28-Dec to 31-Dec Felipe sign for Fiorentina in January 2010 |
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| 08-Jan to 10-Jan Comotto 4th yellow card ban (1 match) |
| M.5 | 14-Jan | | Chievo | | 3-2 | 4-1-3-2 | |
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| 15-Jan to 17-Jan Donadel 4th yellow card ban (1 match) |
| M.6 | 20-Jan | | Lazio | | 3-2 | 4-2-3-1 | In:Frey, Montolivo, Vargas, Gilardino, Out:Avramov, Comotto, Gobbi, Babacar, |
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| 28-Jan to 28-Jan Mutu again positive to a drug check in January 10th (sibutramine) |
| February 2010 |
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| 29-Jan to 18-Apr Mutu suspended by Fiorentina waiting for Federal Judge decisions |
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| 02-Feb to 04-Feb Donadel Coppa Italia ban (1 match) |
| M.7 | 03-Feb | away | Inter | | 1-0 | 4-1-4-1 | In:Comotto, Gamberini, Bolatti, Gobbi, Out:D Silvestri, Krøldrup, Donadel, Mutu, |
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| April 2010 |
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| 05-Feb to 07-Feb Felipe 4th yellow card ban (1 match) |
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| 14-Feb to 16-Apr Gamberini dislocated shoulder |
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| 14-Feb to 04-Mar Santana medial gastrocnemius muscle tear |
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| 18-Feb to 21-Feb Krøldrup 4th yellow card ban (1 match) |
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| 18-Feb to 21-Feb Montolivo 8th yellow card ban (1 match) |
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| 08-Mar to 11-Mar Gobbi red card Champions' League ban (1 match of 3) |
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| 11-Mar to 18-Mar Natali biceps femoris muscle strain |
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| 12-Mar to 05-Apr Marchionni knee trauma, medial collateral ligaments partially involved |
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| 16-Mar to 21-Mar Felipe 8th yellow card ban (1 match) |
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| 22-Mar to 25-Mar Pasqual 4th yellow card ban (1 match) |
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| 29-Mar to 03-Apr Gobbi 4th yellow card ban (1 match) |
| M.8 | 13-Apr | | Inter | | 0-1 | 4-2-3-1 | In:D Silvestri, Krøldrup, Felipe, Zanetti, Marc'ni, Jovetić, Out:Comotto, Gamberini, Pasqual, Bolatti, Santana, Gobbi, |
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| 20-Apr to 25-Apr Gobbi red card ban (1 match) |
| May 2010 |
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| Color References: GK, DF, DM, MF, FW , Unknown Pos |