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Independiente Substitutions at Copa Sudamericana 2021
| Most In | | Most Out | | Martínez, Braian | 3 times | 26 minutes avg | | Herrera, Jonathan (1991) | 3 | 28 | | Palacios, S | 2 | 12 | | Blanco, Domingo | 2 | 12 | | Arregui | 2 | 22 | | Soñora, A | 2 | 5 | | Ortega, T | 2 | 24 | | Asis, G | 1 | 3 | | Pacchini | 1 | 22 | | Menéndez, J | 1 | 16 | | Ostachuk | 1 | 0 | | Roa, A | 1 | 29 | | Rodríguez, Lucas (1993) | 1 | 44 | | González, Lucas (2000) | 1 | 13 | | Márquez, Rodrigo | 1 | 6 |
| | | Palacios, S | 5 times | 78 minutes avg | | Blanco, Domingo | 3 | 71 | | Roa, A | 2 | 76 | | Romero, Lucas (1994) | 2 | 80 | | Togni, G | 2 | 46 | | Velasco, Alan | 2 | 86 | | Rodríguez, Lucas (1993) | 2 | 63 | | Bustos, F | 1 | 87 | | Soñora, A | 1 | 82 | | González, Lucas (2000) | 1 | 46 | | Ayrton Costa | 1 | 58 | | Di Lorenzo, J | 1 | 66 | | Martínez, Braian | 1 | 75 |
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| | 8 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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