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Independiente Substitutions at Copa de la Liga Profesional 2021
| Most In | | Most Out | | Velasco, Alan | 6 times | 26 minutes avg | | Arregui | 5 | 12 | | Roa, A | 5 | 16 | | Herrera, Jonathan (1991) | 5 | 16 | | Martínez, Braian | 3 | 11 | | González, Lucas (2000) | 3 | 22 | | Ortega, T | 3 | 30 | | Blanco, Domingo | 3 | 14 | | Pacchini | 2 | 27 | | Messiniti | 2 | 14 | | Palacios, S | 1 | 17 | | Romero, Lucas (1994) | 1 | 27 | | Soñora, A | 1 | 20 | | Togni, G | 1 | 1 | | Ostachuk | 1 | 4 | | Menéndez, J | 1 | 0 | | Rodríguez, Lucas (1993) | 1 | 29 |
| | | Palacios, S | 8 times | 73 minutes avg | | Menéndez, J | 7 | 74 | | González, Lucas (2000) | 6 | 71 | | Hernández, Pablo | 3 | 67 | | Blanco, Domingo | 3 | 76 | | Velasco, Alan | 3 | 84 | | Ayrton Costa | 2 | 60 | | Romero, Silvio | 2 | 81 | | Romero, Lucas (1994) | 2 | 86 | | Rodríguez, Lucas (1993) | 2 | 68 | | Roa, A | 2 | 71 | | Soñora, A | 1 | 60 | | Barreto, S | 1 | 63 | | Messiniti | 1 | 67 | | Togni, G | 1 | 46 |
| | 15 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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