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Independiente Medellin Substitutions at Apertura 2022
| Most In | | Most Out | | Castrillón, B | 9 times | 19 minutes avg | | Hernández, José (1996) | 7 | 26 | | Pardo, F | 5 | 37 | | Méndez | 5 | 7 | | Valencia, Ever | 5 | 20 | | Cambindo, D | 5 | 15 | | Cuesta, JM | 5 | 13 | | Loaiza, DA | 4 | 22 | | Ricaurte | 4 | 30 | | Mosquera, JD | 4 | 20 | | Rodríguez, Steven | 2 | 0 | | Arboleda, JG | 2 | 6 | | Bueno, DA | 2 | 16 | | Díaz, Yesid | 2 | 44 | | Hernández, V | 2 | 28 | | Díaz, JC (2001) | 2 | 8 | | López, Edwar | 2 | 19 | | Arregui | 1 | 44 | | Gutiérrez, GA | 1 | 17 | | Pons, L | 1 | 18 | | Vásquez, LH | 1 | 73 | | Gómez, Y | 1 | 17 |
| | | Pardo, F | 11 times | 69 minutes avg | | Hernández, V | 9 | 78 | | Méndez | 7 | 64 | | Pineda, Jean | 6 | 77 | | Ricaurte | 5 | 52 | | Arregui | 5 | 82 | | Díaz, JC (2001) | 4 | 76 | | Hernández, José (1996) | 3 | 41 | | Gómez, Y | 3 | 77 | | Loaiza, DA | 3 | 86 | | Moreno, VA | 3 | 57 | | Castrillón, B | 3 | 56 | | Arboleda, JG | 3 | 49 | | Cambindo, D | 2 | 88 | | Mosquera, JD | 2 | 76 | | Pons, L | 1 | 89 | | Valencia, Ever | 1 | 46 | | Gutiérrez, GA | 1 | 73 |
| | 25 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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