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Junior Substitutions at Copa Libertadores 2021
| Most In | | Most Out | | Cetré Angulo | 4 times | 33 minutes avg | | Piedrahita, M | 4 | 19 | | Martínez, HE | 3 | 18 | | Valencia, Carmelo | 3 | 13 | | Rosero, D | 2 | 14 | | Rodríguez, Juan (1992) | 2 | 10 | | González, Luis (1990) | 2 | 18 | | Sambueza, F | 2 | 34 | | Velasco, E | 2 | 4 | | Vásquez, Larry | 1 | 11 | | Pajoy, J | 1 | 27 | | Fuentes, G | 1 | 44 | | Berdugo | 1 | 4 | | Ángel, F | 1 | 21 | | Moreno, Daniel (1995) | 1 | 24 |
| | | Pajoy, J | 5 times | 74 minutes avg | | González, Luis (1990) | 3 | 69 | | Moreno, D | 3 | 82 | | Viáfara, F | 2 | 58 | | Fuentes, G | 2 | 73 | | Martínez, HE | 2 | 80 | | Vásquez, Larry | 2 | 50 | | Sambueza, F | 2 | 64 | | Cetré Angulo | 2 | 84 | | Gutiérrez, Teo | 1 | 68 | | Mera, G | 1 | 62 | | Velasco, E | 1 | 46 | | Hinestroza, F | 1 | 69 | | Borja, MA | 1 | 63 | | Moreno, Daniel (1995) | 1 | 81 | | Rosero, D | 1 | 78 |
| | 10 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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