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Liga de Quito Substitutions at Copa Libertadores 2021
| Most In | | Most Out | | Espinoza, Joseph | 4 times | 14 minutes avg | | Quintero, José | 3 | 10 | | Ayala, Luis | 3 | 23 | | Reasco, DN | 1 | 13 | | Caicedo, Luis (1992) | 1 | 44 | | Muñoz, Adolfo | 1 | 44 | | Piovi, L | 1 | 20 | | Zunino, M | 1 | 31 | | Perlaza, P | 1 | 0 | | Ventura, F | 1 | 18 | | Corozo, Moisés | 1 | 10 |
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| | | Cruz, C | 3 times | 67 minutes avg | | Zunino, M | 2 | 75 | | Piovi, L | 2 | 76 | | Villarruel, L | 2 | 81 | | Quintero, José | 2 | 82 | | Ayala, Luis | 1 | 77 | | Guerra, Franklin | 1 | 46 | | Caicedo, Luis (1992) | 1 | 46 | | Corozo, Moisés | 1 | 92 | | Muñoz, Adolfo | 1 | 59 | | Ordóñez, A | 1 | 80 | | Alcívar, J | 1 | 63 |
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| | 6 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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