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Liga de Quito Substitutions at Copa Sudamericana 2022
| Most In | | Most Out | | Angulo, Nilson | 4 times | 32 minutes avg | | Arce, Jefferson | 4 | 14 | | Quintero, José | 2 | 28 | | Corozo, Moisés | 2 | 5 | | Guerra, Franklin | 2 | 0 | | De Jesús, B | 2 | 2 | | Ortiz, JJ | 1 | 44 | | Scotto, S | 1 | 16 | | Ayala, Luis | 1 | 34 | | López, Marcos (1993) | 1 | 24 | | Hoyos, M | 1 | 44 | | Muñoz, Adolfo | 1 | 3 | | Espinoza, Joseph | 1 | 20 | | Nnachi | 1 | 19 |
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| | | Alvarado, Alexander | 4 times | 78 minutes avg | | Ortiz, JJ | 3 | 65 | | González, Sebastián (2003) | 2 | 72 | | Quintero, José | 2 | 80 | | Hoyos, M | 2 | 82 | | Angulo, Nilson | 2 | 79 | | Scotto, S | 1 | 46 | | Julio, J | 1 | 46 | | Romero, Z | 1 | 80 | | López, Marcos (1993) | 1 | 56 | | Corozo, Moisés | 1 | 71 | | Cruz, C | 1 | 56 | | Muñoz, Adolfo | 1 | 46 | | Zambrano, Ó | 1 | 90 | | Molina, T | 1 | 86 |
| | 8 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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