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Metropolitanos Substitutions at Copa Sudamericana 2021
| Most In | | Most Out | | Mancín | 3 times | 13 minutes avg | | Rosa, G | 3 | 9 | | Hernández, Evelio | 3 | 18 | | González, Albert | 3 | 10 | | Soto, HE | 2 | 26 | | Pavone, T | 2 | 10 | | Antón, I | 2 | 15 | | Acevedo, JA | 1 | 0 | | Rojas, T | 1 | 13 | | Colmenarez, L | 1 | 0 | | González, Luis (1993) | 1 | 27 | | Rentería, S | 1 | 21 | | Flores, RD | 1 | 39 |
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| | | | 8 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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