| Lineups found Starting lineup changes since last game |
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| September 2023 |
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| Coach Howe since 08-Nov-21 |
| M.1 | 19-Sep | away | Milan | | 0-0 | 4-3-3 | |
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| October 2023 |
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 29-Sep to 02-Feb Barnes, H Ankle Injury |
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| 29-Sep to 15-Dec Botman Knee Injury |
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| 29-Sep to 09-Oct Wilson, Callum (1992) Thigh Injury |
| M.2 | 04-Oct | | PSG | | 4-1 | 4-3-3 | In:Lascelles, Almirón, Out:Botman, Murphy, |
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 07-Oct to 09-Oct Gordon, Anthony Yellow Cards |
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| 24-Oct to 06-Nov Miley, L Illness |
| M.3 | 25-Oct | | Dortmund | | 0-1 | 4-3-3 | In:Joelinton, Out:Tonali, |
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| November 2023 |
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| 27-Oct to 20-Feb Anderson, E Back Injury |
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| 27-Oct to 24-Nov Isak Groin Injury |
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| 03-Nov to 10-Mar Targett Thigh Injury |
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| 05-Nov to 27-Jan Murphy, Jacob Shoulder Injury |
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| 06-Nov to 15-Dec Burn Back Injury |
| M.4 | 07-Nov | away | Dortmund | | 2-0 | 4-3-3 | In:Hall, Willock, Livr'to, Wilson, Out:Burn, Almirón, Isak, Gordon, |
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| 10-Nov to 12-Nov Bruno Guimarães Yellow Cards |
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| 10-Nov to 09-Dec Wilson, Callum (1992) Thigh Injury |
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| 24-Nov to 26-Nov Hall, Lewis (2004) Loan agreement |
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| 24-Nov to 09-Dec Longstaff, S Ankle Injury |
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| 27-Nov to 23-Feb Willock, J Achilles Tendon Injury |
| M.5 | 28-Nov | away | PSG | | 1-1 | 4-3-3 | In:Miley, Almirón, Isak, Gordon, Out:Hall, Longstaff, Willock, Wilson, |
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| December 2023 |
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| 02-Dec to 03-May Pope, N Shoulder Injury |
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| 02-Dec to 06-Dec Gordon, Anthony Groin Injury |
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| 10-Dec to 22-Dec Isak Groin Injury |
| M.6 | 13-Dec | | Milan | | 1-2 | 4-3-3 | In:Dúbravka, Wilson, Out:Pope, N, Isak, |
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| February 2024 |
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| 14-Dec to 18-Dec Trippier Knock |
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| 14-Dec to 22-Dec Isak Groin Injury |
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| 16-Dec to 22-Dec Schär Thigh Injury |
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| 16-Dec to 25-Dec Joelinton Thigh Injury |
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| 19-Dec to 22-Dec Gordon, Anthony Calf Injury |
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| 25-Dec to 31-Dec Lascelles Injury |
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| 27-Dec to 02-Feb Wilson, Callum (1992) Calf Injury |
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| 06-Jan to 03-May Joelinton Thigh Injury |
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| 07-Jan to 09-Feb Lascelles Calf Injury |
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| 14-Jan to 29-Jan Almirón, MA Illness |
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| 30-Jan to 23-Feb Isak Groin Injury |
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| 04-Feb to 16-Feb Murphy, Jacob Calf Injury |
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| 11-Feb to 23-Apr Wilson, Callum (1992) Chest Injury |
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| 18-Feb to 23-Feb Schär Wrist Injury |
| March 2024 |
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| 24-Feb to 01-Mar Botman Knock |
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| 10-Mar to 12-Mar Hall, Lewis (2004) Loan agreement |
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| 10-Mar to 12-Mar Trippier Calf Injury |
| April 2024 |
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| 29-Mar to 20-May Botman Knee Injury |
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| 29-Mar to 20-May Miley, L Back Injury |
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| 29-Mar to 10-May Trippier Calf Injury |
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| 01-Apr to 03-Apr Gordon, Anthony Red Card |
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| 01-Apr to 20-May Lascelles Knee Injury |
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| 01-Apr to 03-May Almirón, MA Knee Injury |
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| 01-Apr to 12-Apr Livramento, V Ankle Injury |
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| 01-Apr to 20-May Targett Achilles Tendon Injury |
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| 12-Apr to 20-May Willock, J Achilles Tendon Injury |
| May 2024 |
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| 03-May to 14-May Schär Thigh Injury |
| June 2024 |
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| 14-May to 18-May Wilson, Callum (1992) Thigh Injury |
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| 18-May to 20-May Livramento, V Ankle Injury |
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| 18-May to 20-May Gordon, Anthony Ankle Injury |
| Color References: GK, DF, DM, MF, FW , Unknown Pos |