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Olimpia Substitutions at Copa Libertadores 2021
| Most In | | Most Out | | Santacruz, JF | 5 times | 27 minutes avg | | Rojas, Rodrigo | 4 | 11 | | Camacho, N | 4 | 23 | | Silva, Alejandro | 3 | 36 | | Otálvaro, S | 2 | 38 | | Cáceres, L (1996) | 2 | 13 | | Pitta | 1 | 3 | | López, Edwar | 1 | 35 | | Alcaraz | 1 | 7 | | Ojeda, B | 1 | 44 | | Salcedo, Saúl | 1 | 12 | | Santa Cruz | 1 | 35 | | Sosa, Ramón | 1 | 23 | | González, Walter (1995) | 1 | 0 | | Quintana, H | 1 | 30 | | Cardozo, Fernando | 1 | 11 |
| | | Quintana, H | 5 times | 55 minutes avg | | Recalde, J | 4 | 66 | | Ojeda, B | 3 | 78 | | Cáceres, L (1996) | 2 | 48 | | Salazar, V | 2 | 58 | | Orzusa | 2 | 75 | | González, Derlis (1994) | 2 | 79 | | Otálvaro, S | 1 | 87 | | Santa Cruz | 1 | 55 | | Benítez, Alan | 1 | 73 | | Polenta | 1 | 78 | | Rojas, Rodrigo | 1 | 55 | | Torres, Ivan | 1 | 92 | | Estigarribia, Marcelo (1987) | 1 | 71 | | Silva, Alejandro | 1 | 67 | | Alcaraz | 1 | 70 | | Ortiz, R | 1 | 79 |
| | 10 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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