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River Plate de Asunción Substitutions at Copa Sudamericana 2021
| Most In | | Most Out | | Zeballos, Pablo (1986) | 3 times | 10 minutes avg | | Navarro, Gustavo | 3 | 4 | | Otazú | 2 | 28 | | Sosa, Cristian (1987) | 2 | 12 | | Agüero, E | 1 | 5 | | Quiñónez, A | 1 | 28 | | Gaona, W | 1 | 7 | | Miño, I | 1 | 19 | | Godoy, Diego | 1 | 22 | | Garcete, A | 1 | 7 | | Vera, R | 1 | 20 | | Saldívar | 1 | 34 | | Contrera, A | 1 | 19 | | Bareiro, F | 1 | 3 | | Gallardo, Orlando | 1 | 8 | | Caballero | 1 | 4 | | Bogado, W | 1 | 21 | | Torales, S | 1 | 44 |
| | | Quiñónez, A | 4 times | 77 minutes avg | | González, Marcelo (1996) | 3 | 84 | | Molinas | 2 | 75 | | Godoy, Diego | 2 | 66 | | Pérez, Dionisio | 2 | 87 | | Sosa, Cristian (1987) | 2 | 71 | | Garcete, A | 2 | 84 | | Miño, I | 1 | 63 | | Vera, R | 1 | 68 | | Otazú | 1 | 68 | | Rojas, Nicolas | 1 | 56 | | Zeballos, Pablo (1986) | 1 | 71 | | Saldívar | 1 | 82 | | Gaona, W | 1 | 69 |
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| | 8 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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