| Lineups found Starting lineup changes since last game |
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| August 2011 |
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| Coach Luis Enrique since 08-Jun-11 |
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 07-Aug to 08-Oct Greco, L left thigh |
| November 2011 |
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| 28-Aug to 19-Sep Cicinho, (1980) thigh injury |
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 16-Sep to 18-Sep Cote red card ban (1 match) |
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| 18-Sep to 12-Oct Stekelenburg serious concussion after clash with Inter defender Lùcio |
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| 26-Sep to 08-Oct Gago calf |
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| 29-Sep to 04-Oct Perrotta left ankle straining trauma |
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| 02-Oct to 29-Oct Totti right thigh |
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| 13-Oct to 31-Oct Lobont flexor injury |
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| 14-Oct to 16-Nov Cicinho, (1980) muscle pain |
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| 16-Oct to 29-Oct Rosi left ankle straining trauma |
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| 21-Oct to 23-Oct Kjær red card ban (1 match) |
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| 22-Oct to 29-Oct Pjanić right thigh pain |
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| 30-Oct to 19-Dec Borini right thigh flexor muscle strain |
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| 21-Nov to 01-Dec Rosi ankle bruise |
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| 23-Nov to 01-Dec Totti ankle pain |
| December 2011 |
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| 09-Dec to 12-Dec Gago red card ban (1 match) |
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| 09-Dec to 12-Dec Bojan K red card ban (1 match) |
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| 09-Dec to 12-Dec Juan red card ban (1 match) |
| January 2012 |
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| 16-Dec to 18-Dec Pjanić 4th yellow card ban (1 match) |
| M.5 | 11-Jan | | Fiorentina | | 3-0 | 4-3-1-2 | |
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| M.6 | 24-Jan | away | Juventus | | 3-0 | 4-3-3 | In:Cote, Simplicio, Pjanić, Out:Cicinho, Viviani, Greco, |
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| February 2012 |
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| 07-Feb to 09-Feb Lamela Coppa Italia F.J. ban (2 matches to be played) |
| March 2012 |
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| 17-Feb to 19-Feb Kjær 4th yellow card ban (1 match) |
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| 24-Feb to 26-Feb Totti 4th yellow card ban (1 match) |
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| 02-Mar to 04-Mar Gago 4th yellow card ban (1 match) |
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| 05-Mar to 22-Mar Pjanić left biceps femoris muscle strain |
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| 05-Mar to 05-May Juan medial collateral ligament knee sprain |
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| 08-Mar to 11-Mar Stekelenburg red card ban (1 match) |
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| 15-Mar to 22-Mar Totti biceps femoris muscle strain |
| May 2012 |
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| 23-Mar to 08-Apr Greco, L right thigh flexor muscle pain |
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| 23-Mar to 26-Apr Lobont left knee straining trauma |
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| 25-Mar to 14-Apr Borini left biceps femoris muscle strain |
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| 30-Mar to 01-Apr Heinze 4th yellow card ban (1 match) |
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| 02-Apr to 17-Apr Simplicio right thigh flexor muscle strain |
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| 05-Apr to 10-Apr Totti calf |
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| 23-Apr to 02-May Lamela Federal Judge ban for violent conduct (3 matches) |
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| 23-Apr to 25-Apr Stekelenburg red card ban (1 match) |
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| 23-Apr to 25-Apr Bojan K 4th yellow card ban (1 match) |
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| 27-Apr to 12-May Stekelenburg shoulder |
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| 30-Apr to 08-May Rosi ankle |
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| 12-May to 14-May Taddei 4th yellow card ban (1 match) |
| Color References: GK, DF, DM, MF, FW , Unknown Pos |