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Santos Laguna Substitutions at Apertura 2022
| Most In | | Most Out | | Suárez, L | 9 times | 30 minutes avg | | López, Aldo | 8 | 12 | | Medina, Diego (2001) | 6 | 19 | | González, Jair | 5 | 30 | | Correa, Marcelo | 5 | 32 | | Domínguez, C | 4 | 20 | | Lozano, JR | 4 | 24 | | Cervantes, Alan | 3 | 39 | | Ávila, José | 3 | 12 | | Pizzichillo, F | 2 | 8 | | Preciado, H | 2 | 38 | | Prieto, RdJ | 2 | 33 | | Rodríguez, H | 1 | 45 | | Carrillo, J | 1 | 33 | | Torres, Félix | 1 | 33 | | Preciado, Ayrton | 1 | 32 |
| | | Brunetta | 13 times | 72 minutes avg | | Orrantía | 6 | 63 | | Cervantes, Alan | 5 | 67 | | Gorriarán | 5 | 78 | | González, Jair | 5 | 51 | | Campos, Omar (2002) | 4 | 70 | | Prieto, RdJ | 3 | 50 | | Suárez, L | 3 | 69 | | Torres, Félix | 3 | 47 | | Medina, Diego (2001) | 3 | 64 | | Domínguez, C | 2 | 51 | | Lozano | 1 | 65 | | Pizzichillo, F | 1 | 57 | | Correa, Marcelo | 1 | 76 | | Preciado, H | 1 | 62 | | Aguirre, E | 1 | 80 |
| | 19 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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