| Lineups found Starting lineup changes since last game |
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| August 2010 |
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| Coach Guidolin since 24-May-10 |
| October 2010 |
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 27-Aug to 12-Sep Isla red card ban + 6th yellow card (2 matches for 2010/11 ss.) |
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 27-Sep to 24-Oct Domizzi flexor muscle strain |
| M.3 | 27-Oct | | Padova | | 4-0 | 3-4-1-2 | |
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| 28-Oct to 31-Oct Coda red card ban (1 match) |
| November 2010 |
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| 08-Nov to 11-Nov Zapata, Cr 4th yellow card ban (1 match) |
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| 09-Nov to 25-Nov Zapata, Cr hand fracture |
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| 12-Nov to 19-Nov Pasquale Federal Judge ban for insulting the referee (1 match) |
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| 12-Nov to 14-Nov Pinzi 4th yellow card ban (1 match) |
| M.4 | 24-Nov | | Lecce | | 2-1 | 3-5-2 | In:Zapata, Abdi, Pasquale, Denis, Out:Domizzi, Armero, Fore'ri, F Flores, |
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| December 2010 |
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| January 2011 |
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| 07-Jan to 09-Jan Pinzi red card ban (1 match) |
| M.5 | 19-Jan | away | Sampdoria | | 2-2 | 3-5-2 | In:Inler, D Natale, Out:Morosini, Corradi, |
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| 20-Jan to 16-Feb Angella knee strain |
| April 2011 |
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| 31-Jan to 03-Feb Sánchez , Alexis red card ban (1 match) |
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| 18-Feb to 20-Feb Sánchez , Alexis 4th yellow card ban (1 match) |
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| 03-Mar to 06-Mar Floro Flores Federal Judge ban for insulting the referee (1 match) |
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| 21-Mar to 22-Mar Morosini 4th yellow card ban (1 match) |
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| 25-Mar to 27-Mar Forestieri 4th yellow card ban (1 match) |
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| 01-Apr to 03-Apr Pinzi 8th yellow card ban (1 match) |
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| 06-Apr to 22-Apr Sánchez , Alexis left thigh adductor muscle strain |
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| 08-Apr to 10-Apr Inler 4th yellow card ban (1 match) |
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| 13-Apr to 28-Apr Badu ankle |
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| 15-Apr to 17-Apr Abdi 4th yellow card ban (1 match) |
| May 2011 |
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| 21-Apr to 09-May Domizzi FJ ban for insulting the referee, 8th card ban (3 matches) |
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| 27-Apr to 04-May Sánchez , Alexis left thigh adductor muscle strain |
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| 29-Apr to 09-May Inler FJ ban for protesting 5th yellow card (2 matches) |
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| 29-Apr to 02-May Armero 4th yellow card ban (1 match) |
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| 13-May to 15-May Angella red card ban (1 match) |
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 22-May to 22-May Di Natale Serie A 2010/11 Topscorer (28 goals) |
| Color References: GK, DF, DM, MF, FW , Unknown Pos |