| Lineups found Starting lineup changes since last game |
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| January 2022 |
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 15-Jan to 06-Feb Salah national team |
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| 15-Jan to 24-Jan Keïta, national team |
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 22-Jan to 24-Jan Elliott Ankle Injury |
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| 24-Jan to 10-Feb Oxla'in Illness |
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| 24-Jan to 10-Feb Gomez Illness |
| July 2022 |
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| 22-Feb to 09-Mar R Firmino Muscle Injury |
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| 26-Feb to 06-Mar T Alca'ra Thigh Injury |
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| 11-Mar to 13-Mar Konaté, Knock |
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| 15-Mar to 17-Mar Milner Illness |
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| 15-Mar to 17-Mar Tsimikas Illness |
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| 01-Apr to 04-Apr Keïta, Knee Injury |
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| 17-Apr to 29-Apr Jones Illness |
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| 23-Apr to 09-May R Firmino Foot Injury |
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| 25-Apr to 29-Apr Tsimikas Illness |
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| 16-May to 23-May Fabinho Muscle Injury |
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| 16-May to 21-May Salah Muscle Injury |
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| 16-May to 21-May v Dijk Knee Injury |
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| 21-May to 23-May Gomez Foot Injury |
| 12Jul | | Man.Utd | | 4-0 | Not Conf. | Initial team: Alisson, Mabaya, Phillips, Gomez, Chambers, Morton, Henderson, F Carvalho, Elliott, R Firmino, Díaz, |
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| 21Jul | | Leipzig | | 0-5 | Not Conf. | In:Adrián, Alex'ld, Konaté, v Dijk, Robertson, Keïta, Fabinho, T Alca'ra, Salah,
Out:Alisson, Mabaya, Phillips, Gomez, Chambers, Morton, Henderson, F Carvalho, Elliott, |
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| November 2022 |
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| 05-Aug to 14-Sep Jones Calf Injury |
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| 05-Aug to 14-Sep Kelleher Muscle Injury |
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| 05-Aug to 14-Sep Konaté, Injury |
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| 05-Aug to 14-Sep Oxla'in Muscle Injury |
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| 05-Aug to 14-Aug Tsimikas Knock |
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| 14-Aug to 04-Sep T Alca'ra Hamstring Injury |
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| 14-Aug to 30-Aug Matip Groin Injury |
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| 21-Aug to 01-Sep Núñez, Red Card |
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| 21-Aug to 14-Sep Ramsay Injury |
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| 26-Aug to 14-Sep Keïta, Lacking Match Fitness |
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| 02-Sep to 14-Sep Henderson Thigh Injury |
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| 06-Sep to 11-Sep F Carvalho Thigh Injury |
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| 12-Sep to 14-Sep Robertson Knee Injury |
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| 30-Sep to 17-Oct Jones Leg Injury |
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| 30-Sep to 13-Nov Keïta, Lacking Match Fitness |
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| 30-Sep to 18-Oct Oxla'in Muscle Injury |
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| 30-Sep to 03-Oct Ramsay Injury |
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| 30-Sep to 25-Oct Konaté, Knee Injury |
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| 30-Sep to 10-Oct Robertson Knee Injury |
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| 07-Oct to 13-Nov v Berg Ankle Injury |
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| 11-Oct to 17-Oct Alex'ld Ankle Injury |
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| 11-Oct to 13-Nov Díaz, Knee Injury |
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| 11-Oct to 13-Nov Matip Calf Injury |
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| 21-Oct to 27-Oct Núñez, Muscle Injury |
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| 25-Oct to 28-Oct T Alca'ra Illness |
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| 05-Nov to 11-Nov Milner Head Injury |
| December 2022 |
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| Color References: GK, DF, DM, MF, FW , Unknown Pos |