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| 05-May-23 19:00
Estadio Defensores del Chaco
Ref:Juliadoza
Lm 1:Aquino
Lm 2:Weiler
|
 | Nacional
Fleitas, D 41'
| 1 - 0 | Sportivo Ameliano
|
| |
| 06-May-23 17:00
Feliciano Cáceres
Ref:Méndez, J
Lm 1:Candia
Lm 2:Medina, H
|
 | Sportivo Luqueño
Mendoza, Jorge (1989py) 28'
Fernández, Diego (2002) 53'
Fernández, Diego (2002) 76' 
| 3 - 0 | Guaraní
|
| |
| 06-May-23 19:30
Martín Torres
Ref:Ojeda, D
Lm 1:Onieva
Lm 2:Mercado
|
 | Trinidense
Álvarez, Alex 13'
Arce, Pedro 90'
| 2 - 0 | General Caballero JLM
|
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| 07-May-23 17:00
Luis Alfonso Giagni
Ref:Díaz de Vivar
Lm 1:Britos
Lm 2:Fernández, N
|
 | Resistencia
Da Silva, Nelson 37'
| 1 - 2 | Cerro Porteño
 31' Samudio, B
 og 44' Ruan, VSdJ
|
| |
| 07-May-23 19:30
Parque del Guairá
Ref:Benitez, J
Lm 1:Miranda, G
Lm 2:Arzamendia
|
 | Guaireña FC
Acosta, Marcelo (2000) 15'
| 1 - 0 | Olimpia
|
| |
| 08-May-23 19:00
Luis Alfonso Giagni
Ref:López, J
Lm 1:Cuevas, J
Lm 2:Saldivar, M
|
 | Tacuary
Valdez, I 45'
Valdez, I 51'
Rodríguez, Derlis 66'
| 3 - 0 | Libertad
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