| Player | Position | Lineups |
 | Huntelaar | FW Striker | 34 |
| | Heitinga | DF Centre-back/Defensive midfielder | 33 |
 | Suárez, Luis (1987) | FW Striker | 33 |
| | Stekelenburg | GK | 31 |
| | Emanuelson | MF Left-midfield/Box-to-Box midfielder | 31 |
 | Vertonghen | DF Centre-back/Left-back | 30 |
 | Rommedahl | FW Right-wing | 29 |
 | Gabri, (1979)  | MF Defensive midfielder/Right-back | 26 |
 | de Jong, S | MF Attacking midfielder/Striker | 22 |
| | Vermaelen | DF Centre-back/Left-back | 19 |
 | Bakırcıoğlu | MF Either side midfield/Attacking midfielder | 18 |
 | Ogararu | DF Right-back/Right-midfield | 16 |
| | Perez in 01-Jan | MF Attacking midfielder/Left-wing | 16 |
| | Luque in 25-Aug | FW Striker/Left-wing | 16 |
| | Maduro Out 17-Jan | MF Defensive midfielder/Centre-back | 15 |
 | Davids  | MF Box-to-Box midfielder/Left-midfield | 14 |
| | Bruno Silva in 22-Jan | DF Right-back | 12 |
| | Colin, J | DF Centre-back/Right-back | 12 |
| | Lindgren in 28-Jan | DF Centre-back/Defensive midfielder | 11 |
| | Schilder Out 31-Dec | DF Left-back/Defensive midfielder | 8 |
 | Leonardo, Santiago | FW Either side wing/Striker | 8 |
| | Stam | DF Centre-back/Right-back | 6 |
| | van der Wiel | DF Right-back/Centre-back | 6 |
| | Gentenaar | GK | 5 |
| | Delorge | MF Right-midfield | 4 |
| | Donald, M | MF Box-to-Box midfielder | 3 |
 | Kuffour in 30-Jan | DF Centre-back | 2 |
| | van der Heijden, J | DF Centre-back/Defensive midfielder | 2 |
| | Urzáiz | FW Striker | 2 |
| | Krohn-Dehli | MF Box-to-Box midfielder/Left-midfield | 1 |
| | Sarpong | FW Either side wing/Attacking midfielder | 1 |
| | Heijblok | GK | 0 |
 | Anita | MF Defensive midfielder/Either side back | 0 |
| | Lindenbergh Out 31-Aug | MF Defensive midfielder/Left-back | 0 |
 | Manucharyan | FW Right-wing/Striker | 0 |
| | Mitea | FW Left-wing | 0 |
31 players used
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