| Lineups found Starting lineup changes since last game |
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| August 2010 |
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| Coach Colomba since 21-Oct-09 |
| October 2010 |
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| Coach Magnani since 30-Aug-10 |
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| Coach Malesani since 01-Sep-10 |
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 20-Aug to 08-Sep Manu Gavilán left foot |
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| 24-Aug to 20-Oct Morleo right thigh quadriceps contracture, knee joint involved |
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| 29-Aug to 01-Oct Busce right biceps femoris muscle strain |
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| 09-Sep to 30-Sep Ekdal right ankle straining trauma |
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 19-Oct to 25-Oct Pérez, Diego 4th yellow card ban (1 match) |
| M.3 | 27-Oct | | Modena | | 3-2 | 4-2-3-1 | |
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| November 2010 |
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| M.4 | 25-Nov | away | Cagliari | | 0-3 | 4-2-3-1 | In:Esposito, Morleo, Paponi, Out:Rubin, Pérez, Giménez, |
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| December 2010 |
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| January 2011 |
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 16-Dec Massimo Zanetti appointed new owner |
| M.5 | 18-Jan | away | Napoli | | 2-1 | 3-5-2 | In:Portanova, Busce, Rado'ic, Krhin, J Cruz, Giménez, Out:Moras, Morleo, Mutarelli, Siligardi, Ramírez, Paponi, |
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| 24-Jan to 05-Feb Ramírez, Gastón fractured cheekbone by Lazio defender André Dias |
| April 2011 |
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| 28-Jan to 03-Feb Giménez, Henry Federal Judge ban for violent conduct (2 matches) |
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| 28-Jan to 30-Jan Moras Federal Judge ban for violent conduct (1 match) |
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| 28-Jan to 30-Jan Pérez, Diego 8th yellow card ban (1 match) |
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| 28-Jan to 30-Jan Portanova 4th yellow card ban (1 match) |
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| 07-Feb to 22-Feb Ekdal left thigh biceps femoris muscle strain |
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| 24-Feb to 12-Mar Ekdal left thigh biceps femoris muscle strain |
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| 25-Feb to 28-Feb Ramírez, Gastón 4th yellow card ban (1 match) |
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| 25-Mar to 18-Apr Giménez, Henry right ankle straining trauma |
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| 15-Apr to 17-Apr Pérez, Diego 12th yellow card ban (1 match) |
| May 2011 |
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| 24-Apr to 09-May Busce right biceps femoris muscle strain |
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| 24-Apr to 02-May Pérez, Diego right thigh semitendinosus muscle inflammation |
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| 29-Apr to 10-May Esposito, A right biceps femoris muscle strain |
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| 06-May to 09-May Mutarelli 4th yellow card ban (1 match) |
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| Coach Tardioli since 26-May-11 |
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| Coach Bisoli since 26-May-11 |
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| 13-May to 15-May Ekdal 4th yellow card ban (1 match) |
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| 21-May to 22-May Ramírez, Gastón FJ for insulting, 6th yellow card (1 of 2 matches) |
| Color References: GK, DF, DM, MF, FW , Unknown Pos |