| Lineups found Starting lineup changes since last game |
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| August 2022 |
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| Coach Tuchel since 26-Jan-21 |
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 13-Aug to 26-Aug Kovačić Knee Injury |
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| 20-Aug to 26-Aug Broja, A Injury |
| November 2022 |
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| Coach Hamberg, Björn since 08-Sep-22 |
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| Coach Bruno, Saltor since 08-Sep-22 |
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| Coach Potter since 08-Sep-22 |
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| Coach Reid since 08-Sep-22 |
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 26-Aug to 28-Aug Koulibaly, K Red Card |
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| 29-Aug to 31-Aug Gallagher, C Red Card |
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| 07-Sep to 12-Sep Mendy, Edouard Knee Injury |
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| 30-Sep to 04-Oct Cucurella Illness |
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| 10-Oct to 12-Oct Ziyech Illness |
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| 24-Oct to 01-Nov Koulibaly, K Knee Injury |
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| 01-Nov to 03-Nov Kovačić Muscle Injury |
| M.3 | 09-Nov | away | Man.City | | 2-0 | 3-4-3 | |
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| December 2022 |
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| January 2023 |
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| 26-Dec to 28-Dec Kovačić Rest |
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| 26-Dec to 14-Jan Loftus-Cheek Calf Injury |
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| 26-Dec to 28-Dec Ziyech Rest |
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| 31-Dec to 03-Apr Mendy, Edouard Shoulder Injury |
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| 11-Jan to 22-Jan Sterling, R Thigh Injury |
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| 11-Jan to 05-Mar Pulisic Knee Injury |
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| 14-Jan to 12-Feb Zakaria, D Muscle Injury |
| February 2023 |
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| 10-Feb to 12-Feb Kovačić Calf Injury |
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| 14-Feb to 16-Feb Aubameyang, PE Inactive |
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| 14-Feb to 17-Feb Sterling, R Knee Injury |
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| 25-Feb to 09-Apr Azpilicueta Head Injury |
| Color References: GK, DF, DM, MF, FW , Unknown Pos |