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Santos Laguna Substitutions at Femenil Apertura 2022
| Most In | | Most Out | | Félix, JG | 4 times | 8 minutes avg | | Soto, S | 4 | 13 | | López, BV | 2 | 22 | | Martínez, M | 2 | 10 | | Gomez, E | 2 | 54 | | Peregrina | 1 | 23 | | Curiel, AG | 1 | 34 | | Estrada, KE | 1 | 11 | | de León, LA | 1 | 43 | | Romero, LM | 1 | 9 | | Varela, S | 1 | 9 | | Delgado, D | 1 | 19 |
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| | | Pulido, SO | 4 times | 81 minutes avg | | López, BV | 3 | 66 | | Estrada, KE | 2 | 57 | | Delgado, D | 2 | 76 | | León, B | 2 | 80 | | Félix, DN | 2 | 86 | | Gomez, E | 1 | 58 | | Curiel, AG | 1 | 90 | | Martínez, M | 1 | 46 | | Soto, S | 1 | 81 | | Peraza, C | 1 | 68 | | Varela, S | 1 | 25 |
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| | 7 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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