| | Pts | | GP | W | D | L | GS | GA | Dif | | Home | W | D | L | GS | GA | | Away | W | D | L | GS | GA |
|
| Group A |
  Liverpool | | 10 | | 6 | 3 | 1 | 2 | 11 | 9 | +2 | | 3 | 1 | 1 | 1 | 5 | 5 | | 3 | 2 | 0 | 1 | 6 | 4 |
  Anzhi Makhachkala | | 10 | | 6 | 3 | 1 | 2 | 7 | 5 | +2 | | 3 | 3 | 0 | 0 | 5 | 0 | | 3 | 0 | 1 | 2 | 2 | 5 |
  Young Boys Bern | | 10 | | 6 | 3 | 1 | 2 | 14 | 13 | +1 | | 3 | 2 | 0 | 1 | 9 | 7 | | 3 | 1 | 1 | 1 | 5 | 6 |
  Udinese | | 4 | | 6 | 1 | 1 | 4 | 7 | 12 | -5 | | 3 | 0 | 1 | 2 | 3 | 5 | | 3 | 1 | 0 | 2 | 4 | 7 |
| Group B |
  Viktoria Plzeň | | 13 | | 6 | 4 | 1 | 1 | 11 | 4 | +7 | | 3 | 3 | 0 | 0 | 8 | 1 | | 3 | 1 | 1 | 1 | 3 | 3 |
  Atletico Madrid | | 12 | | 6 | 4 | 0 | 2 | 7 | 4 | +3 | | 3 | 3 | 0 | 0 | 4 | 1 | | 3 | 1 | 0 | 2 | 3 | 3 |
  Academica | | 5 | | 6 | 1 | 2 | 3 | 6 | 9 | -3 | | 3 | 1 | 2 | 0 | 4 | 2 | | 3 | 0 | 0 | 3 | 2 | 7 |
  Hapoel Tel-Aviv | | 4 | | 6 | 1 | 1 | 4 | 4 | 11 | -7 | | 3 | 1 | 0 | 2 | 3 | 5 | | 3 | 0 | 1 | 2 | 1 | 6 |
| Group C |
  Fenerbahçe | | 13 | | 6 | 4 | 1 | 1 | 10 | 7 | +3 | | 3 | 1 | 1 | 1 | 4 | 5 | | 3 | 3 | 0 | 0 | 6 | 2 |
  Borussia Mönchengladbach | | 11 | | 6 | 3 | 2 | 1 | 11 | 6 | +5 | | 3 | 2 | 0 | 1 | 6 | 4 | | 3 | 1 | 2 | 0 | 5 | 2 |
  Olympique de Marseille | | 5 | | 6 | 1 | 2 | 3 | 9 | 11 | -2 | | 3 | 1 | 1 | 1 | 7 | 4 | | 3 | 0 | 1 | 2 | 2 | 7 |
  AEL Limassol | | 4 | | 6 | 1 | 1 | 4 | 4 | 10 | -6 | | 3 | 1 | 1 | 1 | 3 | 1 | | 3 | 0 | 0 | 3 | 1 | 9 |
| Group D |
 FC Girondins de Bordeaux | | 13 | | 6 | 4 | 1 | 1 | 10 | 5 | +5 | | 3 | 3 | 0 | 0 | 7 | 0 | | 3 | 1 | 1 | 1 | 3 | 5 |
 Newcastle United | | 9 | | 6 | 2 | 3 | 1 | 7 | 5 | +2 | | 3 | 2 | 1 | 0 | 5 | 1 | | 3 | 0 | 2 | 1 | 2 | 4 |
 Maritimo | | 6 | | 6 | 1 | 3 | 2 | 4 | 6 | -2 | | 3 | 1 | 2 | 0 | 3 | 2 | | 3 | 0 | 1 | 2 | 1 | 4 |
  Club Brugge | | 4 | | 6 | 1 | 1 | 4 | 6 | 11 | -5 | | 3 | 1 | 1 | 1 | 5 | 4 | | 3 | 0 | 0 | 3 | 1 | 7 |
| Group E |
  Steaua Bucureşti | | 11 | | 6 | 3 | 2 | 1 | 9 | 9 | 0 | | 3 | 2 | 0 | 1 | 4 | 5 | | 3 | 1 | 2 | 0 | 5 | 4 |
 VfB Stuttgart | | 8 | | 6 | 2 | 2 | 2 | 9 | 6 | +3 | | 3 | 0 | 2 | 1 | 2 | 3 | | 3 | 2 | 0 | 1 | 7 | 3 |
  FC Copenhagen | | 8 | | 6 | 2 | 2 | 2 | 5 | 6 | -1 | | 3 | 1 | 1 | 1 | 3 | 4 | | 3 | 1 | 1 | 1 | 2 | 2 |
  Molde FK | | 6 | | 6 | 2 | 0 | 4 | 6 | 8 | -2 | | 3 | 1 | 0 | 2 | 4 | 4 | | 3 | 1 | 0 | 2 | 2 | 4 |
| Group F |
  Dnipro Dnipropetrovsk | | 15 | | 6 | 5 | 0 | 1 | 16 | 8 | +8 | | 3 | 3 | 0 | 0 | 9 | 1 | | 3 | 2 | 0 | 1 | 7 | 7 |
 Napoli | | 9 | | 6 | 3 | 0 | 3 | 12 | 12 | 0 | | 3 | 2 | 0 | 1 | 9 | 5 | | 3 | 1 | 0 | 2 | 3 | 7 |
  PSV Eindhoven | | 7 | | 6 | 2 | 1 | 3 | 8 | 7 | +1 | | 3 | 1 | 1 | 1 | 5 | 3 | | 3 | 1 | 0 | 2 | 3 | 4 |
  AIK | | 4 | | 6 | 1 | 1 | 4 | 5 | 14 | -9 | | 3 | 1 | 0 | 2 | 4 | 5 | | 3 | 0 | 1 | 2 | 1 | 9 |
| Group G |
 RC Genk | | 12 | | 6 | 3 | 3 | 0 | 9 | 4 | +5 | | 3 | 2 | 1 | 0 | 5 | 1 | | 3 | 1 | 2 | 0 | 4 | 3 |
 FC Basel | | 9 | | 6 | 2 | 3 | 1 | 7 | 4 | +3 | | 3 | 2 | 1 | 0 | 6 | 2 | | 3 | 0 | 2 | 1 | 1 | 2 |
  MOL Féhérvár FC | | 6 | | 6 | 2 | 0 | 4 | 6 | 8 | -2 | | 3 | 2 | 0 | 1 | 5 | 2 | | 3 | 0 | 0 | 3 | 1 | 6 |
 Sporting Lisbon | | 5 | | 6 | 1 | 2 | 3 | 4 | 10 | -6 | | 3 | 1 | 2 | 0 | 3 | 2 | | 3 | 0 | 0 | 3 | 1 | 8 |
| Group H |
 Rubin Kazan | | 14 | | 6 | 4 | 2 | 0 | 10 | 3 | +7 | | 3 | 3 | 0 | 0 | 6 | 0 | | 3 | 1 | 2 | 0 | 4 | 3 |
 Inter Milan | | 11 | | 6 | 3 | 2 | 1 | 11 | 9 | +2 | | 3 | 1 | 2 | 0 | 5 | 4 | | 3 | 2 | 0 | 1 | 6 | 5 |
  Neftchi Baku | | 3 | | 6 | 0 | 3 | 3 | 4 | 8 | -4 | | 3 | 0 | 1 | 2 | 2 | 5 | | 3 | 0 | 2 | 1 | 2 | 3 |
  Partizan Belgrade | | 3 | | 6 | 0 | 3 | 3 | 3 | 8 | -5 | | 3 | 0 | 2 | 1 | 2 | 4 | | 3 | 0 | 1 | 2 | 1 | 4 |
| Group I |
 Olympique Lyonnais | | 16 | | 6 | 5 | 1 | 0 | 14 | 8 | +6 | | 3 | 3 | 0 | 0 | 6 | 2 | | 3 | 2 | 1 | 0 | 8 | 6 |
 Sparta Praha | | 9 | | 6 | 2 | 3 | 1 | 9 | 6 | +3 | | 3 | 2 | 1 | 0 | 7 | 3 | | 3 | 0 | 2 | 1 | 2 | 3 |
 Athletic Club | | 5 | | 6 | 1 | 2 | 3 | 7 | 9 | -2 | | 3 | 0 | 2 | 1 | 3 | 4 | | 3 | 1 | 0 | 2 | 4 | 5 |
 Ironi Kiryat Shmona | | 2 | | 6 | 0 | 2 | 4 | 6 | 13 | -7 | | 3 | 0 | 1 | 2 | 4 | 7 | | 3 | 0 | 1 | 2 | 2 | 6 |
| Group J |
 Lazio | | 12 | | 6 | 3 | 3 | 0 | 9 | 2 | +7 | | 3 | 2 | 1 | 0 | 4 | 0 | | 3 | 1 | 2 | 0 | 5 | 2 |
 Tottenham Hotspur | | 10 | | 6 | 2 | 4 | 0 | 8 | 4 | +4 | | 3 | 2 | 1 | 0 | 6 | 2 | | 3 | 0 | 3 | 0 | 2 | 2 |
  Panathinaikos | | 5 | | 6 | 1 | 2 | 3 | 4 | 11 | -7 | | 3 | 1 | 2 | 0 | 3 | 2 | | 3 | 0 | 0 | 3 | 1 | 9 |
  NK Maribor | | 4 | | 6 | 1 | 1 | 4 | 6 | 10 | -4 | | 3 | 1 | 1 | 1 | 5 | 5 | | 3 | 0 | 0 | 3 | 1 | 5 |
| Group K |
 Bayer Leverkusen | | 13 | | 6 | 4 | 1 | 1 | 9 | 2 | +7 | | 3 | 2 | 1 | 0 | 4 | 0 | | 3 | 2 | 0 | 1 | 5 | 2 |
 Metalist Kharkiv | | 13 | | 6 | 4 | 1 | 1 | 9 | 3 | +6 | | 3 | 3 | 0 | 0 | 7 | 1 | | 3 | 1 | 1 | 1 | 2 | 2 |
 Rosenborg BK | | 6 | | 6 | 2 | 0 | 4 | 7 | 10 | -3 | | 3 | 1 | 0 | 2 | 4 | 5 | | 3 | 1 | 0 | 2 | 3 | 5 |
  SK Rapid Wien | | 3 | | 6 | 1 | 0 | 5 | 4 | 14 | -10 | | 3 | 1 | 0 | 2 | 2 | 6 | | 3 | 0 | 0 | 3 | 2 | 8 |
| Group L |
 Hannover 96 | | 12 | | 6 | 3 | 3 | 0 | 11 | 8 | +3 | | 3 | 2 | 1 | 0 | 5 | 3 | | 3 | 1 | 2 | 0 | 6 | 5 |
 Levante | | 11 | | 6 | 3 | 2 | 1 | 10 | 5 | +5 | | 3 | 2 | 1 | 0 | 6 | 2 | | 3 | 1 | 1 | 1 | 4 | 3 |
 Helsingborgs IF | | 4 | | 6 | 1 | 1 | 4 | 9 | 12 | -3 | | 3 | 0 | 1 | 2 | 4 | 7 | | 3 | 1 | 0 | 2 | 5 | 5 |
 Twente Enschede | | 4 | | 6 | 0 | 4 | 2 | 5 | 10 | -5 | | 3 | 0 | 2 | 1 | 3 | 5 | | 3 | 0 | 2 | 1 | 2 | 5 |
| Round of 32 |
| Levante 3 - Olympiacs 0 14-Feb-13 21-Feb-13 Olympiacs 0 - Levante 1 |
| Basel 2 - Dnipro 0 14-Feb-13 21-Feb-13 Dnipro 1 - Basel 1 |
| Stuttgart 1 - Genk 1 14-Feb-13 21-Feb-13 Genk 0 - Stuttgart 2 |
| Napoli 0 - V.Plzeň 3 14-Feb-13 21-Feb-13 V.Plzeň 2 - Napoli 0 |
| D.Kyiv 1 - Bordeaux 1 14-Feb-13 21-Feb-13 Bordeaux 1 - D.Kyiv 0 |
| Sparta 0 - Chelsea 1 14-Feb-13 21-Feb-13 Chelsea 1 - Sparta 1 |
| Inter 2 - CFR Cluj 0 14-Feb-13 21-Feb-13 CFR Cluj 0 - Inter 3 |
| Ajax 2 - FCSB 0 14-Feb-13 21-Feb-13 FCSB 2 - Ajax 0 |
| Newcastle 0 - Metalist 0 14-Feb-13 21-Feb-13 Metalist 0 - Newcastle 1 |
| Tottenham 2 - Lyon 1 14-Feb-13 21-Feb-13 Lyon 1 - Tottenham 1 |
| Zenit 2 - Liverpool 0 14-Feb-13 21-Feb-13 Liverpool 3 - Zenit 1 |
| Anzhi 3 - Hannover 1 14-Feb-13 21-Feb-13 Hannover 1 - Anzhi 1 |
| BATE 0 - Fenerbhce 0 14-Feb-13 21-Feb-13 Fenerbhce 1 - BATE 0 |
| A.Madrid 0 - Rubin 2 14-Feb-13 21-Feb-13 Rubin 0 - A.Madrid 1 |
| Leverkusn 0 - Benfica 1 14-Feb-13 21-Feb-13 Benfica 2 - Leverkusn 1 |
| Mgladbach 3 - Lazio 3 14-Feb-13 21-Feb-13 Lazio 2 - Mgladbach 0 |
| Round of 16 |
| Anzhi 0 - Newcastle 0 07-Mar-13 14-Mar-13 Newcastle 1 - Anzhi 0 |
| FCSB 1 - Chelsea 0 07-Mar-13 14-Mar-13 Chelsea 3 - FCSB 1 |
| Tottenham 3 - Inter 0 07-Mar-13 14-Mar-13 Inter 4 - Tottenham 1 |
| Benfica 1 - Bordeaux 0 07-Mar-13 14-Mar-13 Bordeaux 2 - Benfica 3 |
| Basel 2 - Zenit 0 07-Mar-13 14-Mar-13 Zenit 1 - Basel 0 |
| Stuttgart 0 - Lazio 2 07-Mar-13 14-Mar-13 Lazio 3 - Stuttgart 1 |
| V.Plzeň 0 - Fenerbhce 1 07-Mar-13 14-Mar-13 Fenerbhce 1 - V.Plzeň 1 |
| Levante 0 - Rubin 0 07-Mar-13 14-Mar-13 Rubin 2 - Levante 0 |
| Quarter-finals |
| Fenerbhce 2 - Lazio 0 04-Apr-13 11-Apr-13 Lazio 1 - Fenerbhce 1 |
| Tottenham 2 - Basel 2 04-Apr-13 11-Apr-13 Basel 2 - Tottenham 2 |
| Benfica 3 - Newcastle 1 04-Apr-13 11-Apr-13 Newcastle 1 - Benfica 1 |
| Chelsea 3 - Rubin 1 04-Apr-13 11-Apr-13 Rubin 3 - Chelsea 2 |
| Semi-finals |
| Fenerbhce 1 - Benfica 0 25-Apr-13 02-May-13 Benfica 3 - Fenerbhce 1 |
| Basel 1 - Chelsea 2 25-Apr-13 02-May-13 Chelsea 3 - Basel 1 |
| Final |
| Benfica 1 - Chelsea 2 15-May-13 |
|